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The Food and Drug Administration, FDA, has approved the drug Vivitrol for your treatment of opioid dependence as outlined by a news release by them on 10-12-2010.

Using two separate drugs to lose weight can be very effective you'll find combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people that go through it one should err to the side of caution and permit the FDA do its job and demand some investigation be done in order that the public recognizes the side effects and risks of the medications before we drive them. Keep in mind that drug companies are in business to generate money and that they would say anything to keep people on their own medications.

Researchers found that participants taking this drug for any year, dropped a few pounds within a month and have kept the load off during the entire 56 weeks of the study. Contrave is a combination in the drugs naltrexone and bupropion, which generally seems to reflect a fresh trend of weight-loss drugs which can be made up of multiple active ingredient, which may make them far better and safer.

Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and therefore it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that by using a combination of pills is starting to become popular is the fact that as of right now there are no long term prescription diet pills that have been licensed by the FDA besides orlistat. The truly disturbing part is doctors are prescribing these combinations of medications and some of the combinations have been rejected or have yet to be authorized by the FDA.

Seizures really are a side effect with Contrave and shouldn't be taken in people with seizure disorders. The drug also can raise hypertension and heartbeat, and shouldn't be used in those with a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured before starting the drug and throughout therapy using the drug.

The FDA also warned that Contrave can raise blood pressure and pulse rate and must not used in patients with uncontrolled high blood pressure levels, in addition to by you are not heart-related and cerebrovascular (blood vessel dysfunction impacting the brain) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded in the clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert physicians and patients to the increased chance of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are actually reported in patients taking bupropion for stop smoking.


The most common side effects reported with Contrave include nausea, constipation, headache, vomiting, dizziness, insomnia, dry mouth, and diarrhea.

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